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Topic Title: ChemDraw 16 Mac does neither open .cdx nor .sdf files
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Created On: 3/27/2020 7:04 PM
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 3/27/2020 7:04 PM
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Joined: 3/27/2020

Hi, my ChemDraw 16 Mac does not open .cdx or .sdf files after I followed advice from the Cambridgesoft support group to fix another issue with my ChemDraw and Catalina (freezing on saving). I followed this advice:

Any help would be appreciated.

 3/30/2020 9:52 PM
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Posts: 691
Joined: 2/25/2009

ChemDraw 16.0 not compatible on Mac OSX 10.15.x Also versions prior to 19.0 are not supported with Mac OSX 10.15.x

Please find the supported Mac OSX for ChemDraw v16.0 - 19.0

v16.0 - Mac OSX 10.10.x, Mac OSX 10.11.x and Mac OSX 10.12.x
v17.0 - Mac OSX 10.12.x and Mac OSX 10.13.x
v18.x - Mac OSX 10.13.x and Mac OSX 10.14..x
v19.x - Mac OSX 10.13.x, Mac OSX 10.14.x and Mac OSX 10.15.x

So we recommend to retest the problem with v19.0.

If you still run in to any problem, please visit to submit a ticket (or send an email to, to get assistance from our Tech Support Team


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